The Brains

 were one of the four cliques apart of the clique twist introduced on Big Brother 11. The three members were Chima Simone, Michele Noonan, and Ronnie Talbott.

Trivia

 * Ronnie is the only member of the clique to have a normal HoH reign.
 * Michele's reign was cut short due to Chima's expulsion.
 * Jeff used the Coup d'Etat during Chima's reign, pulling both of her nominations off of the block.